scphylo.tl.huntress#

scphylo.tl.huntress(df_input, alpha, beta, n_threads=1)[source]#

Solving using HUNTRESS.

HUNTRESS: Provably fast intratumor heterogeneity inference from single-cell sequencing data

Parameters

  • df_input (pandas.DataFrame) – Input genotype matrix in which rows are cells and columns are mutations. Values inside this matrix show the presence (1), absence (0) and missing entires (3).

  • alpha (float) – False positive error rate.

  • beta (float) – False negative error rate.

  • n_threads (int, optional) – Number of threads, by default 1

Returns

A conflict-free matrix in which rows are cells and columns are mutations. Values inside this matrix show the presence (1) and absence (0).

Return type

pandas.DataFrame