scphylo.tl.onconem

scphylo.tl.onconem(df_input, alpha, beta)

Solving using OncoNEM.

Inferring tumor evolution from single-cell sequencing data [OncoNEM].

Parameters:

• df_input (pandas.DataFrame) – Input genotype matrix where 0 is absent, 1 is present and 3 is missing.

• alpha (float) – False positive rate.

• beta (float) – False negative rate.

Returns:

Conflict-free genotype matrix where 0 is absent, 1 is present.

Return type:

pandas.DataFrame

Examples

Reconstruct tree by OncoNEM

Reconstruct tree by OncoNEM